Description

2-((S)-5-Amino-2-(((Benzyloxy)Carbonyl)Amino)-5-Oxopentanamido)-3-Phenylpropanoic Acid Methyl Ester is a sophisticated, optically active peptide derivative designed for advanced chemical synthesis. This compound serves as a critical protected intermediate, enabling the precise construction of complex peptide sequences with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of therapeutic peptides targeting metabolic disorders, oncology, and infectious diseases.
• Peptidomimetic Research: Used to create and study peptidomimetic compounds, which mimic the structure and function of natural peptides with improved stability and bioavailability.
• Bioconjugation Chemistry: Employed in the development of peptide-drug conjugates (PDCs) and other bioconjugates for targeted drug delivery systems.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or modified peptides used as probes to study protein-protein interactions and enzyme mechanisms.
• Academic & R&D Synthesis: A valuable reagent for academic research and contract research organizations (CROs) exploring new synthetic methodologies and peptide-based chemistry.

Basic Information

Product Name	2-((S)-5-Amino-2-(((Benzyloxy)Carbonyl)Amino)-5-Oxopentanamido)-3-Phenylpropanoic Acid Methyl Ester
CAS No.	14317-85-2
Molecular Formula	C24H28N4O6
Molecular Weight	468.50 g/mol
Synonyms	Z-L-Glutamyl-L-phenylalanine methyl ester; N2-[(Benzyloxy)carbonyl]-L-glutaminyl-L-phenylalanine methyl ester; Cbz-L-Gln-L-Phe-OMe; Z-Gln-Phe-OMe; Methyl (2S)-2-[[(2S)-5-amino-2-[(benzyloxy)carbonylamino]-5-oxopentanoyl]amino]-3-phenylpropanoate; L-Phenylalanine, N-[N-[N-[(benzyloxy)carbonyl]-L-glutaminyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of this high-purity peptide intermediate adheres to stringent quality protocols suitable for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to confirm identity, chiral purity, and chemical integrity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to ensure full traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S,S isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.