Description

Carbobenzoxy-Glycyl-Glycyl-Tyrosine Methyl Ester is a protected tripeptide derivative, specifically a Cbz-protected precursor, widely used in solid-phase peptide synthesis (SPPS). This compound is valued for its role as a key building block in the controlled assembly of longer, more complex peptide sequences, ensuring high coupling efficiency and minimal racemization. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of therapeutic peptides and peptidomimetics for drug discovery and development.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected fragment for the efficient, sequential construction of custom peptide sequences in research and GMP manufacturing.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies, protease activity assays, and metabolic pathway investigations.
• Antibiotic & Hormone Synthesis: A precursor in the production of complex bioactive peptides, including certain antibiotic and hormone analogs.
• Material Science: Employed in the development of peptide-based biomaterials, hydrogels, and surface coatings.

Basic Information

Product Name	Carbobenzoxy-Glycyl-Glycyl-Tyrosine Methyl Ester
CAS No.	14317-81-8
Molecular Formula	C22H25N3O7
Molecular Weight	443.45 g/mol
Synonyms	Z-Gly-Gly-Tyr-OMe; Cbz-Gly-Gly-Tyr-OMe; N-Carbobenzoxy-glycyl-glycyl-L-tyrosine methyl ester; Benzyloxycarbonyl-Gly-Gly-Tyr-OMe; Z-Gly-Gly-L-Tyr-OMe; Cbz-Gly-Gly-L-Tyr-OMe; (S)-Methyl 2-((2-(2-((benzyloxy)carbonylamino)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate; CBZ-Gly-Gly-Tyr-OCH3
EINECS	Contact for details

Quality Control

Our Carbobenzoxy-Glycyl-Glycyl-Tyrosine Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.