Description

D-Alanine Methyl Ester Hydrochloride is a chiral, non-natural amino acid derivative widely utilized as a critical building block in organic synthesis and pharmaceutical research. Its primary value lies in providing a protected D-alanine moiety, essential for constructing peptides and peptidomimetics with specific stereochemistry. This compound is particularly important for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially antibiotics, enzyme inhibitors, and peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the D-alanine residue, which can confer metabolic stability and alter biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and for probing the structure and function of proteins and enzymes.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in the preparation of complex, enantiomerically pure molecules.
• Agrochemical Development: Used in research for creating novel chiral herbicides, fungicides, or plant growth regulators.
• Food & Flavor Chemistry: Potential use in the synthesis of certain flavor enhancers or nutritional supplements, subject to appropriate grade and regulatory compliance.

Basic Information

Product Name	D-Alanine Methyl Ester Hydrochloride
CAS No.	14316-06-4
Molecular Formula	C4H9NO2 • HCl
Molecular Weight	139.58 g/mol (Free base: 103.12 g/mol)
Synonyms	Methyl D-alaninate hydrochloride; (R)-2-Aminopropionic acid methyl ester hydrochloride; D-2-Aminopropanoic acid methyl ester hydrochloride; Methyl (R)-2-aminopropanoate hydrochloride; D-Ala-OMe • HCl; (R)-Alanine methyl ester hydrochloride; D-α-Aminopropionic acid methyl ester hydrochloride; Alanine methyl ester, D-, hydrochloride
EINECS	Contact for details

Quality Control

Our D-Alanine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing specific results for identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.