Description

4-Epichlortetracycline Hydrochloride is a high-purity chemical reference standard, specifically qualified for use as a secondary standard in analytical applications. This compound is critical for ensuring the accuracy, precision, and traceability of analytical methods, particularly in quality control and research laboratories. It is primarily utilized by professionals in the pharmaceutical, biotechnology, and analytical chemistry sectors who require reliable reference materials for method validation, calibration, and impurity profiling.

Application

• Pharmaceutical Quality Control (QC): Serves as a secondary reference standard for the assay and impurity determination of tetracycline-class antibiotics.
• Analytical Method Development & Validation: Used to calibrate instruments and validate High-Performance Liquid Chromatography (HPLC) and other chromatographic methods.
• Research & Development: Employed in biochemical and pharmacological studies investigating tetracycline derivatives and their properties.
• Regulatory Compliance Testing: Supports testing protocols to meet standards set by pharmacopoeias (e.g., USP, EP) and regulatory bodies.
• Impurity Identification and Quantification: Acts as a known impurity or degradation product marker in stability studies of related drug substances.

Basic Information

Product Name	4-Epichlortetracycline Hydrochloride (Canbe Used As Secondary Standard)
CAS No.	14297-93-9
Molecular Formula	C22H23ClN2O8 • HCl
Molecular Weight	515.34 g/mol
Synonyms	4-Epichlortetracycline HCl; 4-Epichlortetracycline Dihydrochloride; 4-Epi-chlortetracycline Hydrochloride; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-7-chloro-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Hydrochloride; 4-Epi-CTC HCl; Chlortetracycline EPI Isomer Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Epichlortetracycline Hydrochloride is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets stringent specifications for identity, purity, and potency, making it suitable for use as a secondary standard. A comprehensive Certificate of Analysis (COA) detailing all test results, including chromatographic purity and assay, is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle the container with care to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.