Description

Bz-Lys-Ome Hcl is a protected amino acid derivative, specifically the benzyloxycarbonyl (Cbz or Z) protected ester of L-lysine methyl ester hydrochloride. This compound serves as a crucial building block in peptide synthesis and organic chemistry, offering a versatile handle for the controlled elongation of peptide chains. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the production of peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled incorporation of lysine residues into peptide sequences.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptides and peptide conjugates.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Labeling: The reactive amine (after deprotection) and ester functionalities allow for the creation of labeled peptides or peptide-polymer conjugates.
• Research & Development: Essential for academic and industrial research in medicinal chemistry, biochemistry, and proteomics.
• Production of Custom Peptides: Used by CROs and CDMOs specializing in the manufacture of peptides for therapeutic and diagnostic applications.

Basic Information

Product Name	Bz-Lys-Ome Hcl
CAS No.	14280-01-4
Molecular Formula	C15H23ClN2O4
Molecular Weight	330.81 g/mol
Synonyms	Nα-Cbz-L-lysine methyl ester hydrochloride; Nα-Z-L-lysine methyl ester hydrochloride; Nα-Carbobenzoxy-L-lysine methyl ester hydrochloride; (S)-Methyl 2-((((benzyloxy)carbonyl)amino)-6-aminohexanoate hydrochloride; Z-Lys-OMe·HCl; Cbz-L-Lys-OMe·HCl; Benzyloxycarbonyl-L-lysine methyl ester hydrochloride; N6-Benzyloxycarbonyl-L-lysine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Bz-Lys-Ome Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the high standards required for pharmaceutical R&D and GMP-guided production. Comprehensive Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +18.0° (c=1 in methanol)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.