Description

3β,14-Dihydroxy-16β-(3-Methyl-1-Oxobutoxy)-5β,14β-Card-20(22)-Enolide CAS NO 14259-53-1 is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional groups make it an essential building block for the research and development of novel cardiovascular therapeutics. This compound is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of specialized cardiac glycosides and related therapeutic agents.
• Medicinal Chemistry Research: Used as a reference standard and a core scaffold for structure-activity relationship (SAR) studies in cardiovascular drug discovery.
• Biochemical Research: Employed in studies investigating the mechanism of action of Na+/K+-ATPase inhibitors.
• Fine Chemical Synthesis: Serves as a chiral building block for the production of complex, biologically active molecules.
• Reference Standard: Utilized in analytical laboratories for method development, calibration, and quality control of related pharmaceutical products.

Basic Information

Product Name	3β,14-Dihydroxy-16β-(3-Methyl-1-Oxobutoxy)-5β,14β-Card-20(22)-Enolide
CAS No.	14259-53-1
Molecular Formula	C30H44O7
Molecular Weight	516.67 g/mol
Synonyms	3β,14-Dihydroxy-16β-(3-methylbutanoyloxy)-5β,14β-card-20(22)-enolide; 16β-(3-Methyl-1-oxobutoxy)-3β,14-dihydroxy-5β,14β-card-20(22)-enolide; 3β,14-Dihydroxy-16β-(3-methylbutyryloxy)-5β,14β-card-20(22)-enolide; 16β-(3-Methylbutyryl)gitoxigenin; Gitoxigenin 16β-(3-methylbutyrate); A derivative of Gitoxigenin; Cardiac glycoside intermediate
EINECS	Contact for details

Quality Control

Our 3β,14-Dihydroxy-16β-(3-Methyl-1-Oxobutoxy)-5β,14β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.