Description

4-Ethynylaniline is a versatile aromatic amine building block characterized by its reactive ethynyl (acetylene) and aniline functional groups. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced materials and complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules designed for targeted therapies.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Monomer for the production of conjugated polymers and advanced organic electronic materials, such as those used in OLEDs and sensors.
• Cross-coupling Reactions: Essential substrate in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Used to synthesize novel nitrogen-containing ligands for homogeneous catalysis.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized dyes and colorants.
• Academic & Industrial R&D: Valuable reagent for exploratory chemistry and process development in fine chemical synthesis.

Basic Information

Product Name	4-Ethynylaniline
CAS No.	14235-81-5
Molecular Formula	C8H7N
Molecular Weight	117.15 g/mol
Synonyms	4-Aminophenylacetylene; 4-Ethynylbenzenamine; p-Ethynylaniline; 1-Amino-4-ethynylbenzene; 4-(Aminomethyl)phenylacetylene (common misnomer); 4-Aminobenzeneacetylene; 4-Ethynyl-phenylamine; p-Aminophenylacetylene
EINECS	Contact for details

Quality Control

Our 4-Ethynylaniline is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.