Description

2',5'-Dideoxyadenosylcobalamin is a specialized, biologically active form of vitamin B12, also known as an adenosylcobalamin analog. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a coenzyme in enzymatic reactions, particularly those involving molecular rearrangements. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in advanced metabolic studies, enzyme mechanism investigations, and the development of novel therapeutic agents or diagnostic kits.

Application

• Biochemical Research: Serves as a critical coenzyme standard or substrate in studies of methylmalonyl-CoA mutase and other B12-dependent enzymes.
• Pharmaceutical Reference Standard: Used as a high-purity analytical reference material for quality control and method development in drug manufacturing.
• Diagnostic Kit Component: Employed in the formulation of clinical diagnostic assays for measuring vitamin B12 levels or related metabolic disorders.
• Enzymology Studies: Essential for investigating the mechanism of adenosylcobalamin-dependent isomerase reactions.
• Nutritional Science: Used in advanced research to understand the specific metabolic pathways and bioavailability of different cobalamin forms.
• Academic & Institutional Research: A key reagent for universities and research institutes focusing on cofactor chemistry, microbiology, and metabolic engineering.

Basic Information

Product Name	2',5'-Dideoxyadenosylcobalamin
CAS No.	14220-72-5
Molecular Formula	C72H100CoN18O17P
Molecular Weight	1579.6 g/mol
Synonyms	Adenosylcobalamin 2',5'-Dideoxy Derivative; 2',5'-Dideoxyadenosyl Cobalamin; Coenzyme B12 Analog; 5'-Deoxy-5'-adenosylcobalamin Derivative; DBC; AdoCbl Analog; Vitamin B12 Coenzyme Analog; Cobamamide Derivative
EINECS	Contact for details

Quality Control

Our 2',5'-Dideoxyadenosylcobalamin is produced and handled under strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, UV-Vis, and NMR to ensure identity, purity, and stability. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and compliance. We support research and production needs with materials suitable for use as reference standards under current Good Manufacturing Practice (cGMP) principles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic and strictly light-sensitive nature, the product must be handled in a controlled environment with minimal exposure to air and moisture. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Dark red to brown crystalline powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (UV-Vis)	Spectrum characteristic of adenosylcobalamin analogs
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.