Description

Emetine Hcl CAS NO 14198-59-5 is a high-purity alkaloid hydrochloride salt derived from ipecac, serving as a critical active pharmaceutical ingredient (API) and a vital reference standard in research. Its primary value lies in its potent anti-amoebic and emetic properties, making it essential for therapeutic and investigative applications. This compound is particularly needed by pharmaceutical manufacturers, clinical research organizations, and analytical laboratories for drug development, quality control, and biochemical studies.

Application

• Pharmaceutical API: Used in the formulation of anti-amoebic medications for the treatment of specific parasitic infections.
• Reference Standard: Serves as a certified reference material (CRM) for the identification and assay of emetine in pharmaceutical quality control (QC) and quality assurance (QA).
• Biochemical Research: Employed as a protein synthesis inhibitor in molecular biology and cell culture studies to investigate cellular mechanisms.
• Clinical Toxicology: Utilized in research related to its emetic effects and the study of ipecac syrup components.
• Analytical Chemistry: Acts as a standard for method development and validation in chromatographic analyses (e.g., HPLC, LC-MS).

Basic Information

Product Name	Emetine Hydrochloride
CAS No.	14198-59-5
Molecular Formula	C₂₉H₄₀N₂O₄ • HCl
Molecular Weight	553.12 g/mol
Synonyms	Emetine HCl; Emetine Hydrochloride Hydrate; (-)-Emetine Hydrochloride; Ipecine Hydrochloride; Cephaeline Methyl Ether Hydrochloride; NSC 33669; 2,3-Didehydroemetine-1',2'-dicarboxylic acid, 6',7',10,11-tetramethoxy-, methyl ester, hydrochloride, (1'R)-
EINECS	Contact for details

Quality Control

Our Emetine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and spectroscopy, to ensure it meets stringent standards suitable for pharmaceutical and research use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.