Description

6-Chloro-3-Methylisoquinoline is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its fused ring structure and halogen substituent, which make it a key intermediate for constructing complex molecules with specific functionalities. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging its bioactive isoquinoline scaffold.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized dyes and pigments due to the chromophoric nature of the isoquinoline system.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and the discovery of new chemical entities.
• Catalyst Ligand Development: Investigated for use as a ligand in transition metal catalysis to facilitate challenging organic transformations.

Basic Information

Product Name	6-Chloro-3-Methylisoquinoline
CAS No.	14123-76-3
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	3-Methyl-6-chloroisoquinoline; 6-Chloro-3-methyl-isoquinoline; Isoquinoline, 6-chloro-3-methyl-; 6-Chloro-3-methylisoquinoline; 6-Chloro-3-methyl-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Methylisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.