Description

4-(Trifluoromethyl)-DL-Phenylalanine is a non-natural, fluorinated amino acid derivative of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile building block, where the trifluoromethyl group imparts unique electronic and steric properties to target molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and the creation of novel peptides and bio-conjugates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and oncology research.
• Medicinal Chemistry & Drug Discovery: Used to incorporate fluorine into lead compounds to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced herbicides and pesticides with enhanced activity and environmental profile.
• Peptide Modification: Enables the synthesis of fluorinated peptide analogs for biochemical studies and potential therapeutic applications.
• Bioconjugation & Probe Development: Utilized in creating labeled compounds and molecular probes for imaging and diagnostic assays.
• Material Science: Acts as a monomer or additive in the development of specialty polymers with tailored surface properties.

Basic Information

Product Name	4-(Trifluoromethyl)-DL-Phenylalanine
CAS No.	14091-16-8
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	DL-4-(Trifluoromethyl)phenylalanine; (±)-2-Amino-3-[4-(trifluoromethyl)phenyl]propanoic Acid; α-Amino-4-(trifluoromethyl)benzenepropanoic Acid; 4-(Trifluoromethyl)phenylalanine; 4-CF3-DL-Phe; 4-Trifluoromethyl-DL-phenylalanine; (RS)-2-Amino-3-(4-trifluoromethylphenyl)propionic acid; DL-p-(Trifluoromethyl)phenylalanine
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)-DL-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Optical Purity (Enantiomeric Excess)	DL-Racemate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.