Description

4-Chlorothieno[2,3-D]Pyrimidine is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need it for its versatility in nucleophilic aromatic substitution and cross-coupling reactions, enabling the creation of new thienopyrimidine-based compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thienopyrimidine scaffold's bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its fused ring system and electron-deficient character.
• Chemical Biology & Proteomics: Employed in the design of chemical probes and affinity tags for studying protein function and enzyme activity.
• Dye & Pigment Synthesis: Acts as an intermediate for creating novel heterocyclic dyes with specific optical properties.
• Academic & Contract Research: Essential for method development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Chlorothieno[2,3-D]Pyrimidine
CAS No.	14080-59-2
Molecular Formula	C6H3ClN2S
Molecular Weight	170.62 g/mol
Synonyms	4-Chlorothieno[2,3-d]pyrimidine; 4-Chloro-thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-; 4-Chloro-5-thia-1,3,7-triazaindene; 4-Chloro-5-thia-1,3,7-triaza-indene; 4-Chloro-thieno[2,3-d]pyrimidin; 4-Chloro-5-thia-1,3,7-triazainden; 4-Chloro-5-thia-1,3,7-triaza-1H-indene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized to confirm identity and purity, with key parameters typically monitored by HPLC, NMR, and GC-MS. Certificates of Analysis (COA) are available upon request, providing batch-specific data. We adhere to a strict quality management system to ensure supply reliability and product consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.