Description

H-Gly-Oipr Hcl is a protected amino acid derivative, specifically the hydrochloride salt of glycine with an isopropyl ester protecting group. This compound is a crucial building block in peptide synthesis, offering enhanced solubility and stability for complex coupling reactions. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled elongation of peptide chains in automated synthesizers.
• Solution-Phase Peptide Synthesis: Used in classical coupling methodologies for producing custom peptides and peptide fragments.
• Pharmaceutical Intermediate: Serves as a critical raw material in the production of peptide-based drugs and diagnostic agents.
• Biochemical Research: Employed in academic and industrial labs for studying protein structure-function relationships and enzyme mechanisms.
• Protecting Group Strategy: The isopropyl ester group provides orthogonal protection, allowing for selective deprotection in multi-step synthetic sequences.

Basic Information

Product Name	H-Gly-Oipr Hcl
CAS No.	14019-62-6
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	Glycine, isopropyl ester, hydrochloride; Isopropyl glycinate hydrochloride; Glycine isopropyl ester HCl; H-Gly-OiPr·HCl; 2-Aminoacetic acid isopropyl ester hydrochloride; Gly-Oipr·HCl; Aminoacetic acid isopropyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-Gly-Oipr Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.