Description

Rifampin Quinone (50 Mg) is a key chemical derivative of the antibiotic rifampin, specifically its quinone form. This compound is essential for pharmaceutical research and development, particularly in the study of antibiotic mechanisms, resistance, and the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in antimicrobial drug development and quality control processes. CAS NO 13983-13-6.

Application

• Pharmaceutical Reference Standard: Serves as a critical standard for the identification, assay, and impurity profiling of rifampin and related compounds in pharmacopeial testing (e.g., USP, EP).
• Antibiotic Research & Development: Used as a key intermediate or analytical marker in studies investigating the structure-activity relationships, metabolism, and degradation pathways of rifamycin-class antibiotics.
• Impurity Standard: Employed in the qualification and quantification of rifampin quinone as a specified impurity in rifampin active pharmaceutical ingredient (API) and finished drug products.
• Biochemical Research: Utilized in enzymatic and microbiological assays to study bacterial RNA polymerase inhibition and the development of antibiotic resistance.
• Analytical Method Development: Acts as a calibrant in developing and validating HPLC, LC-MS, and other chromatographic methods for antibiotic analysis.
• Chemical Synthesis: Functions as a specialized building block or precursor in the synthetic chemistry of novel rifamycin derivatives.

Basic Information

Product Name	Rifampin Quinone (50 Mg)
CAS No.	13983-13-6
Molecular Formula	C43H58N4O12
Molecular Weight	822.95 g/mol
Synonyms	Rifampicin Quinone; Rifamycin SV Quinone; 25-Deacetyl-23-(hydroxymethyl)-12,17,21-trihydroxy-2-methoxy-4,10,16,20-tetramethyl-9,23-dioxo-8,24-dioxa-1,7,11,15-tetraazapentacyclo[15.7.1.1³,¹⁵.0³,⁷.0¹¹,¹⁵]pentacosa-3,5,12,14,16,18,20-heptaen-13-yl acetate; 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin Quinone; Rifampin Q; Antibiotic Rifampicin Quinone
EINECS	Contact for details

Quality Control

Our Rifampin Quinone is produced and controlled under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances. Certificates of Analysis (COA) detailing all test results and specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.