Description

1-Cyano-4-Fluoronaphthalene is a specialized fluorinated naphthalene derivative that serves as a versatile building block in advanced organic synthesis. Its molecular structure, featuring both a cyano and a fluorine substituent, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated organic semiconductors, liquid crystal compounds, and light-emitting materials in display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific characteristics such as thermal stability, chemical resistance, or altered refractive index.
• Dye & Pigment Chemistry: Utilized in the synthesis of advanced fluorinated dyes and pigments for high-performance applications.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and material science research.

Basic Information

Product Name	1-Cyano-4-Fluoronaphthalene
CAS No.	13916-99-9
Molecular Formula	C₁₁H₆FN
Molecular Weight	171.17 g/mol
Synonyms	4-Fluoro-1-naphthalenecarbonitrile; 4-Fluoronaphthalene-1-carbonitrile; 1-Cyano-4-fluoronaphthalene; 4-Fluoro-1-cyanonaphthalene; 1-Naphthalenecarbonitrile, 4-fluoro-; NSC 406914; 4-Fluoro-1-naphthonitrile
EINECS	Contact for details

Quality Control

Our 1-Cyano-4-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.