Description

Coenzyme B12 CAS NO 13870-90-1 is a biologically active form of Vitamin B12, also known as adenosylcobalamin, which serves as an essential cofactor in enzymatic reactions. This high-purity compound is critical for ensuring optimal metabolic function in various biochemical pathways. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and advanced research sectors for formulating high-grade supplements, diagnostic reagents, and cell culture media.

Application

• Pharmaceutical Formulations: As an active pharmaceutical ingredient (API) or key intermediate in injectable and oral vitamin B12 supplements and medications.
• Nutraceutical & Dietary Supplements: A premium-grade ingredient for high-efficacy capsules, tablets, and liquid supplements targeting energy metabolism and neurological health.
• Biochemical Research & Cell Culture: An essential growth factor and coenzyme in microbiological assays, metabolic studies, and specialized cell culture media formulations.
• Diagnostic Reagents: Used in the production of clinical diagnostic kits and reagents for measuring vitamin B12 levels and related metabolic functions.
• Enzyme Stabilization: Employed in industrial biotechnology to stabilize and enhance the activity of B12-dependent enzymes in biocatalytic processes.
• Veterinary Applications: Incorporated into animal feed supplements and veterinary pharmaceuticals to prevent and treat B12 deficiencies.

Basic Information

Product Name	Coenzyme B12
CAS No.	13870-90-1
Molecular Formula	C72H100CoN18O17P
Molecular Weight	1579.58 g/mol
Synonyms	Adenosylcobalamin; Coenzyme B12; Dibencozide; AdoCbl; Cobamamide; 5'-Deoxyadenosylcobalamin; Vitamin B12 Coenzyme; Adenosylcobalamin Coenzyme
EINECS	237-627-6

Quality Control

Our Coenzyme B12 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is tested against rigorous specifications, including identity, potency, and impurity profiles, utilizing advanced analytical techniques like HPLC. Certificates of Analysis (COA) are provided and can be tailored to meet specific pharmacopoeial standards (e.g., USP, EP) or customer requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is strictly light-sensitive and hygroscopic; prolonged exposure to light, air, or moisture must be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Dark red crystalline powder or crystals
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.