Description

2-Bromo-2,3,3,3-Tetrafluoropropionic Acid is a highly fluorinated organic acid derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a valuable reagent for introducing fluorinated motifs into target molecules, which is essential for modifying physical and biological properties. This compound is particularly sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as in materials science for creating specialty polymers and surface-active agents.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms can enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, pesticides, and fungicides that benefit from the unique properties of fluorinated compounds.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated monomers used in liquid crystal displays (LCDs) and dielectric materials.
• Polymer Modification: Acts as a functional monomer or chain-transfer agent to incorporate fluorine into polymers, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to introduce the 2-bromo-2,3,3,3-tetrafluoropropionyl moiety into complex organic frameworks.
• Surface Active Agent Precursor: Used to synthesize fluorinated surfactants and coatings that offer superior oil and water repellency.

Basic Information

Product Name	2-Bromo-2,3,3,3-Tetrafluoropropionic Acid
CAS No.	13859-31-9
Molecular Formula	C3HBrF4O2
Molecular Weight	224.93 g/mol
Synonyms	2-Bromo-2,3,3,3-tetrafluoropropanoic Acid; α-Bromo-α,β,β,β-tetrafluoropropionic Acid; BTPA; 2-Bromo-2,3,3,3-tetrafluoropropionate; NSC 163066; Propionic acid, 2-bromo-2,3,3,3-tetrafluoro-; Perfluorobromopropionic Acid (historical)
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-2,3,3,3-Tetrafluoropropionic Acid is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and strong acid nature, the container must be kept tightly sealed to exclude moisture and stored separately from bases and reactive materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.