Description

Boc-Sar-Oh CAS NO 13734-36-6 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of sarcosine (N-methylglycine). This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where it is used to introduce the sarcosine residue while protecting the amine functionality. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of novel peptides, peptidomimetics, and bioactive compounds.

Application

• Peptide Synthesis Building Block: A key intermediate for incorporating the N-methylglycine (sarcosine) residue into peptide chains using Boc-chemistry strategies.
• Pharmaceutical Research: Used in the R&D of therapeutic peptides where sarcosine residues can influence conformation, stability, and biological activity.
• Peptidomimetic Design: Essential for creating modified peptide analogs with enhanced metabolic stability or receptor selectivity.
• Bioconjugation Chemistry: Acts as a spacer or linker component in the synthesis of peptide-based conjugates for drug delivery or diagnostics.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry and peptide science.
• Fine Chemical Production: Serves as a starting material or intermediate in the multi-step synthesis of complex organic molecules.

Basic Information

Product Name	Boc-Sar-Oh
CAS No.	13734-36-6
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	N-(tert-Butoxycarbonyl)sarcosine; Boc-Sarcosine; Boc-N-methylglycine; (2-{[(tert-Butoxy)carbonyl](methyl)amino}acetic acid); N-Methyl-N-(tert-butoxycarbonyl)glycine; N-Boc-sarcosine; BOC-SAR-OH; N-tert-Butoxycarbonylsarcosine
EINECS	Contact for details

Quality Control

Our Boc-Sar-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	86 - 90 °C
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.