Description

2,4-Difluorobenzenesulfonamide is a high-purity, fluorinated aromatic sulfonamide building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluoro-substituted aromatic ring contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials, where the sulfonamide group can impart specific chemical or physical properties.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes and enzyme inhibitors used in mechanistic studies and target identification.
• Ligand & Catalyst Development: Utilized in the synthesis of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,4-Difluorobenzenesulfonamide
CAS No.	13656-60-5
Molecular Formula	C6H5F2NO2S
Molecular Weight	193.17 g/mol
Synonyms	Benzenesulfonamide, 2,4-difluoro-; 2,4-Difluorobenzene-1-sulfonamide; 2,4-Difluorophenylsulfonamide; 1,3-Difluoro-4-sulfamoylbenzene; 2,4-DFBSA; 2,4-Difluorobenzenesulphonamide; 2,4-Difluorophenylsulfonylamide
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full batch traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.