Description

Angiotensin III, Human is a bioactive heptapeptide fragment of the renin-angiotensin system, playing a critical role in blood pressure regulation and aldosterone secretion. This high-purity peptide is essential for advanced life science research and pharmaceutical development, offering a reliable tool for studying cardiovascular physiology and receptor mechanisms. It is primarily utilized by researchers in pharmacology, endocrinology, and biotechnology for in vitro assays, target validation, and as a reference standard.

Application

• Biomedical Research: Used as a key reagent in studies investigating the renin-angiotensin system (RAS), hypertension, and cardiovascular diseases.
• Pharmacological Assays: Serves as a reference standard and agonist in receptor binding studies and functional assays for AT1 and AT2 receptors.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and target validation for novel cardiovascular and renal therapeutics.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (e.g., ELISA) for angiotensin peptide quantification.
• Academic Research: A fundamental tool for university and institutional labs studying hormone regulation, signal transduction, and peptide metabolism.
• Biotechnology Production: Acts as a critical raw material or intermediate in the synthesis of more complex peptide-based compounds.

Basic Information

Product Name	Angiotensin III, Human
CAS No.	13602-53-4
Molecular Formula	C₄₁H₆₂N₁₂O₁₀
Molecular Weight	899.0 g/mol
Synonyms	Angiotensin III; Asp-Arg-Val-Tyr-Ile-His-Pro; [Asp1, Val5]-Angiotensin II (3-8); Angiotensin (3-8); AIII; Human Angiotensin III; DRVYIHP; Angiotensin II (3-8) fragment
EINECS	Contact for details

Quality Control

Our Angiotensin III, Human is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, ensuring it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.