Description

n-tert-Butyloxycarbonyl-L-Threonine, Compound With Dicyclohexylamine is a protected amino acid derivative widely used in peptide synthesis. This compound is critical for researchers and manufacturers who require high-purity, stable building blocks for complex organic and pharmaceutical synthesis. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for the development of novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Boc-protected L-threonine derivative for the sequential assembly of peptide chains, preventing unwanted side reactions.
• Solution-Phase Peptide Synthesis: Used in classical solution methods for constructing peptide fragments and complex natural products.
• Pharmaceutical Intermediate: An essential raw material in the research and production of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation and Labeling: Employed in the modification of peptides and proteins for research, diagnostic, or therapeutic targeting purposes.
• Combinatorial Chemistry Libraries: Used to generate diverse arrays of peptide-like compounds for high-throughput screening in drug discovery.
• Academic and R&D Laboratories: A fundamental reagent for studying peptide structure, function, and for methodological development in organic chemistry.

Basic Information

Product Name	n-tert-Butyloxycarbonyl-L-Threonine, Compound With Dicyclohexylamine
CAS No.	13564-70-0
Molecular Formula	C19H36N2O5
Molecular Weight	372.50 g/mol
Synonyms	Boc-L-Threonine Dicyclohexylamine Salt; Boc-Thr-OH·DCHA; (2S,3R)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxybutanoic acid compound with dicyclohexylamine; tert-Butoxycarbonyl-L-threonine dicyclohexylammonium salt; N-Boc-L-threonine DCHA salt; L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-, compound with N-cyclohexylcyclohexanamine (1:1); Boc-Thr-DCHA; N-α-tert-Butyloxycarbonyl-L-threonine dicyclohexylamine salt
EINECS	Contact for details

Quality Control

Our n-tert-Butyloxycarbonyl-L-Threonine DCHA salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]20/D	-15° to -18° (c=1 in methanol)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.