Description

Boc-o-Benzyl-L-Tyrosine 4-Nitrophenyl Ester is a protected amino acid derivative specifically designed as an activated ester for peptide synthesis. This compound is a critical building block that enables efficient and controlled coupling reactions, ensuring high yields and minimal racemization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and bioconjugates.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester for the controlled incorporation of protected tyrosine residues into peptide chains.
• Solution-Phase Peptide Synthesis: For the synthesis of short peptides and peptide fragments in solution, offering flexibility in coupling strategies.
• Medicinal Chemistry Research: A key intermediate in the design and synthesis of peptide-based drug candidates and bioactive compounds.
• Bioconjugation: Used to attach peptides or tyrosine-containing motifs to other molecules, such as proteins, polymers, or surfaces.
• Chemical Biology Probes: Synthesis of labeled or modified peptides for studying biological processes and protein interactions.
• Custom Peptide Production: An essential reagent for contract research organizations (CROs) and manufacturers producing custom peptides at scale.

Basic Information

Product Name	Boc-o-Benzyl-L-Tyrosine 4-Nitrophenyl Ester
CAS No.	13512-59-9
Molecular Formula	C27H28N2O7
Molecular Weight	492.52 g/mol
Synonyms	Boc-Tyr(Bzl)-ONp; N-(tert-Butoxycarbonyl)-O-benzyl-L-tyrosine 4-nitrophenyl ester; Boc-O-benzyl-L-tyrosine p-nitrophenyl ester; (2S)-3-(4-{[(Benzyloxy)carbonyl]oxy}phenyl)-2-{[(2-methylpropan-2-yl)oxycarbonyl]amino}propanoic acid 4-nitrophenyl ester; Boc-L-Tyrosine(OBzl)-ONp; Boc-Tyr(OBzl)-ONp; tert-Butoxycarbonyl-O-benzyl-L-tyrosine 4-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Boc-o-Benzyl-L-Tyrosine 4-Nitrophenyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive analytical data, including HPLC purity, optical rotation, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) is supplied with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.