Description

[1S,2R]-trans-2-Aminocyclohexanol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its defined stereochemistry, which is critical for synthesizing enantiomerically pure molecules in medicinal chemistry and asymmetric synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial Research: Employed in chemical biology and medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	[1S,2R]-trans-2-Aminocyclohexanol Hydrochloride
CAS No.	13374-31-7
Molecular Formula	C6H14ClNO
Molecular Weight	151.64 g/mol
Synonyms	(1S,2R)-2-Aminocyclohexanol Hydrochloride; trans-2-Amino-1-cyclohexanol Hydrochloride; (1S,2R)-1-Amino-2-hydroxycyclohexane Hydrochloride; (1S,2R)-2-Amino-cyclohexan-1-ol Hydrochloride; (1S,2R)-2-Aminocyclohexyl Alcohol Hydrochloride; (1S,2R)-Aminocyclohexanol HCl; (1S,2R)-ACH HCl
EINECS	Contact for details

Quality Control

Our [1S,2R]-trans-2-Aminocyclohexanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and commercial use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed-upon standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.