Description

Carbamic Acid, n-[3-[(4S)-2,5-Dioxo-4-Oxazolidinyl]Propyl]-, Phenylmethyl Ester is a specialized chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. Its core value lies in providing a stereochemically defined scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Research: Used to incorporate constrained, heterocyclic amino acid analogs into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Protease Inhibitor Development: Employed in the design and synthesis of inhibitors for various protease enzymes.
• Chemical Biology Probes: Utilized to create labeled or tagged molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	Carbamic Acid, n-[3-[(4S)-2,5-Dioxo-4-Oxazolidinyl]Propyl]-, Phenylmethyl Ester
CAS No.	13296-21-4
Molecular Formula	C14H16N2O5
Molecular Weight	292.29 g/mol
Synonyms	Benzyl N-[3-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]propyl]carbamate; (S)-4-(3-((Benzyloxycarbonyl)amino)propyl)oxazolidine-2,5-dione; Cbz-L-BAPA; N-Carbobenzoxy-L-β-aspartic acid anhydride; L-β-Aspartic acid, N-(benzyloxycarbonyl)-, anhydride; Z-L-β-Aspartic anhydride; Z-β-Asp-OH anhydride; N-Cbz-L-β-aspartic anhydride
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[3-[(4S)-2,5-Dioxo-4-Oxazolidinyl]Propyl]-, Phenylmethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by multiple analytical techniques including HPLC, chiral HPLC, NMR, and MS to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.