Description

Dansyl-Putrescine is a high-purity, fluorescently labeled derivative of the biogenic polyamine putrescine, widely recognized by its CAS registry number 13285-10-4. This compound serves as a critical biochemical probe and analytical standard for the sensitive detection and quantification of polyamine metabolism and transport in biological systems. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, life sciences, and diagnostic reagent manufacturing sectors.

Application

• Biochemical Research & Assay Development: Used as a fluorescent tracer in studies of polyamine uptake, biosynthesis, and catabolism in cell cultures and tissues.
• HPLC & LC-MS Analytical Standards: Serves as a primary reference standard for the chromatographic quantification of putrescine and related polyamines.
• Enzyme Activity Assays: Employed as a substrate or product in fluorometric assays for enzymes like ornithine decarboxylase and polyamine oxidases.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for monitoring polyamine levels, which can be biomarkers for certain cellular processes.
• Pharmaceutical R&D: Utilized in drug discovery programs targeting polyamine pathways, relevant to oncology, parasitology, and neurology.
• Fluorescence Labeling & Conjugation: Acts as a dansyl donor for labeling biomolecules to study protein-polyamine interactions via fluorescence spectroscopy or microscopy.

Basic Information

Product Name	Dansyl-Putrescine
CAS No.	13285-10-4
Molecular Formula	C18H27N3O2S
Molecular Weight	349.49 g/mol
Synonyms	N-(5-Aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide; 1,4-Diaminobutane Dansyl Derivative; Dansylcadaverine analog; DNS-Putrescine; D-Put; 5-(Dimethylamino)naphthalene-1-sulfonyl-1,4-diaminobutane; N1-(5-Dimethylaminonaphthalene-1-sulfonyl)putrescine
EINECS	Contact for details

Quality Control

Our Dansyl-Putrescine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive analytical and research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for fine chemical production to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Fluorescence Properties	Conforms (Ex/Em ~330-340 nm/~510-520 nm)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.