Description

n-Amyl-n-Methylnitrosamine is a specific nitrosamine compound with the CAS number 13256-07-0. This chemical is of significant interest in research and development, particularly for its utility as a critical intermediate and reference standard. It is primarily sought by professionals in the pharmaceutical, chemical research, and analytical sectors who require high-purity, well-characterized materials for method development, toxicology studies, and process chemistry.

Application

• Pharmaceutical Research & Impurity Profiling: Serves as a crucial reference standard for the identification and quantification of nitrosamine impurities (e.g., N-Nitrosodimethylamine, NDMA) in active pharmaceutical ingredients (APIs) and finished drug products, ensuring compliance with stringent regulatory limits.
• Chemical Synthesis Intermediate: Acts as a specialized building block in organic synthesis for the development of novel compounds in research laboratories.
• Toxicological & Carcinogenicity Studies: Used in academic and industrial research to study the metabolic pathways, biological effects, and risk assessment of nitrosamine compounds.
• Analytical Method Development: Employed by QC/QA laboratories to develop, validate, and calibrate highly sensitive analytical methods such as GC-MS, LC-MS/MS, and HPLC for trace-level nitrosamine analysis.
• Regulatory Compliance Testing: Essential for testing raw materials, water, and consumer products to meet global regulatory standards set by agencies like the FDA, EMA, and ICH.
• Material Science Research: Investigated for its properties and interactions in specialized material science applications.

Basic Information

Product Name	n-Amyl-n-Methylnitrosamine
CAS No.	13256-07-0
Molecular Formula	C₆H₁₄N₂O
Molecular Weight	130.19 g/mol
Synonyms	N-Methyl-N-nitroso-1-pentanamine; N-Methyl-N-nitrosoamylamine; N-Nitroso-N-methylpentylamine; N-Nitroso-N-methyl-n-amylamine; N-Methyl-N-nitroso-n-amylamine; N-Amyl-N-methylnitrosamine; Pentylmethylnitrosamine; NMAmA
EINECS	Contact for details

Quality Control

Every batch of our n-Amyl-n-Methylnitrosamine is manufactured and handled under strict quality management systems. We provide comprehensive analytical data to support its use as a high-purity reference material. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to meet the exacting requirements of research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is between 2°C and 8°C. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, yellow to amber liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.