Description

n-(3,4-Dimethoxyphenethyl)-2,2,3,3,4,4,4-Heptafluorobutyramide CAS NO 13230-87-0 is a specialized fluorinated amide compound designed for advanced chemical synthesis and research. This high-value intermediate is critical for introducing unique fluorinated moieties into target molecules, significantly altering their physical, chemical, and biological properties. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and material science researchers developing next-generation products with enhanced stability, bioavailability, or specific activity profiles.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, leveraging the fluorinated chain for improved metabolic stability and membrane permeability.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and pesticides where the heptafluorobutyryl group can enhance lipophilicity and environmental persistence of the active compound.
• Material Science Precursor: Employed in the creation of specialty polymers, surface coatings, and liquid crystals, where fluorination imparts valuable properties like oil/water repellency, chemical resistance, and thermal stability.
• Bioconjugation & Probe Synthesis: Acts as a reagent for modifying peptides, proteins, or other biomolecules in biochemical research, often used to create fluorescent probes or affinity labels.
• Organic Synthesis Building Block: Provides a versatile handle for medicinal and synthetic chemists to construct complex molecular architectures through amide coupling and further functionalization of the dimethoxyphenethyl amine moiety.

Basic Information

Product Name	n-(3,4-Dimethoxyphenethyl)-2,2,3,3,4,4,4-Heptafluorobutyramide
CAS No.	13230-87-0
Molecular Formula	C₁₆H₁₆F₇NO₃
Molecular Weight	403.29 g/mol
Synonyms	N-[2-(3,4-Dimethoxyphenyl)ethyl]-2,2,3,3,4,4,4-heptafluorobutanamide; 2,2,3,3,4,4,4-Heptafluoro-N-[2-(3,4-dimethoxyphenyl)ethyl]butanamide; 3,4-Dimethoxyphenethylamine Heptafluorobutyramide; Heptafluorobutyric Acid (3,4-Dimethoxyphenethyl)amide; HFB-DMPEA Amide; 13230-87-0; Perfluorobutyryl Homoveratrylamine
EINECS	Contact for details

Quality Control

Our n-(3,4-Dimethoxyphenethyl)-2,2,3,3,4,4,4-Heptafluorobutyramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.