Description

3-Chloro-L-Alanine is a halogenated, non-proteinogenic amino acid derivative of L-alanine. This compound serves as a versatile chiral building block and a key intermediate in the synthesis of more complex bioactive molecules. It is particularly valuable in pharmaceutical research and fine chemical manufacturing for applications requiring specific stereochemistry. The product is supplied under stringent quality control to ensure batch-to-batch consistency for industrial and research use.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of enzyme inhibitors, antibiotics, and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for enzymes like tryptophan synthase and D-amino acid oxidase.
• Agrochemical Synthesis: Serves as a chiral synthon in the production of advanced herbicides and plant growth regulators.
• Peptide Modification: Incorporated into synthetic peptides to introduce chloro-functional groups, altering their biological activity and stability.
• Diagnostic Reagent Development: Employed in the formulation of specialized reagents for clinical diagnostics and assay kits.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective chemical reactions.

Basic Information

Product Name	3-Chloro-L-Alanine
CAS No.	13215-35-5
Molecular Formula	C₃H₆ClNO₂
Molecular Weight	123.54 g/mol
Synonyms	(S)-2-Amino-3-chloropropanoic acid; L-3-Chloroalanine; (S)-3-Chloroalanine; Chloro-L-alanine; β-Chloro-L-alanine; 3-Chloroalanine; L-β-Chloroalanine; 3-Chloro-DL-alanine (related)
EINECS	Contact for details

Quality Control

Our 3-Chloro-L-Alanine is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. Key parameters such as chiral purity, chemical purity, and impurity profiles are strictly controlled. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.