Description

Physalaemin C-Terminal Heptapeptide is a bioactive peptide fragment derived from the potent neuropeptide physalaemin, known for its specific receptor binding and physiological activity. This high-purity synthetic peptide is critical for advanced biochemical research and pharmaceutical development, offering a valuable tool for studying tachykinin receptor pathways and related biological mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuropharmacology, peptide chemistry, and drug discovery programs.

Application

• Biochemical Research: As a reference standard and active agent in studies investigating tachykinin (NK1) receptor binding, activation, and signal transduction.
• Pharmacological Studies: Used in vitro and in vivo to explore smooth muscle contraction, vasodilation, and inflammatory responses mediated by related peptide pathways.
• Drug Discovery: Serves as a key intermediate or pharmacophore model for the design and synthesis of novel peptide-based therapeutics targeting neurokinin receptors.
• Diagnostic Development: Potential use in the development of assay kits and diagnostic tools for research into peptide-related disorders.
• Academic Research: A vital reagent for universities and research labs focusing on neuropeptides, structure-activity relationships (SAR), and peptide hormone function.

Basic Information

Product Name	Physalaemin C-Terminal Heptapeptide
CAS No.	13198-06-6
Molecular Formula	C36H55N11O10S
Molecular Weight	826.0 g/mol
Synonyms	Physalaemin (6-11); H-Phe-Tyr-Pro-Leu-Met-NH2; Physalaemin C-terminal hexapeptide amide; [Tyr6, Pro7]-Substance P (6-11); Pyr-Pro-Asn-Pro-Asn-Arg-Phe-Tyr-Pro-Leu-Met-NH2 (fragment); Tachykinin peptide fragment; NK1 receptor ligand fragment
EINECS	Contact for details

Quality Control

Every batch of Physalaemin C-Terminal Heptapeptide is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and consistency suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity (by HPLC), and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.