Description

Dimethyl Adipimidate is a bifunctional crosslinking reagent belonging to the class of imido esters. This compound is valued for its ability to react with primary amines under mild conditions, forming stable amidine bonds, which is critical for creating covalent linkages in complex molecular structures. It is an essential tool for researchers and manufacturers in the life sciences and material chemistry sectors who require precise and reliable protein-protein or protein-nucleic acid conjugation. Its utility extends to applications demanding robust and specific intermolecular attachments.

Application

• Bioconjugation and Crosslinking: A key reagent for covalently linking proteins, antibodies, or enzymes to other biomolecules, solid supports (e.g., agarose beads), or fluorescent probes for diagnostic assays and affinity chromatography.
• Immunogen Preparation: Used to conjugate haptens to carrier proteins, enhancing their immunogenicity for the production of specific antibodies in research and therapeutic development.
• Immobilization of Biomolecules: Facilitates the stable attachment of enzymes or other bioactive molecules to various matrices for use in biosensors, bioreactors, and diagnostic kits.
• Structural Biology Studies: Employed in the analysis of protein quaternary structure and protein-protein interactions through crosslinking experiments followed by mass spectrometry.
• Polymer and Material Science: Serves as a monomer or crosslinker in the synthesis of specialized polymers, hydrogels, and functional materials with tailored properties.
• Nucleic Acid Research: Can be used to crosslink proteins to DNA or RNA, aiding in the study of transcription factors and other DNA-binding protein complexes.

Basic Information

Item	Details
Product Name	Dimethyl Adipimidate
CAS No.	13139-70-3
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	Dimethyl Adipimidate; Adipimidic Acid Dimethyl Ester; Dimethyl Adipimidate Dihydrochloride (common salt form); DMA; Hexanedioic Acid, 1,6-Dimethyl Ester, Imide; Bis(methyl) Adipimidate; Adipimidate Dimethyl Ester; NSC 112192
EINECS	Contact for details

Quality Control

Our Dimethyl Adipimidate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere (e.g., nitrogen or argon) and store the container in a desiccator to prevent moisture absorption, which can compromise product integrity. Typical recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.