Description

N2-Chloroacetyl-Glutamine is a high-purity, synthetically derived glutamine derivative, characterized by its chloroacetyl-protected amine group. This compound is a critical building block in organic synthesis and pharmaceutical research, offering a reactive site for further chemical modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs and other bioactive molecules.
• Bioconjugation Reagent: Used for modifying proteins, peptides, and other biomolecules in biochemical research.
• Organic Synthesis Building Block: Serves as a protected glutamine derivative for constructing complex organic compounds in medicinal chemistry.
• Proteomics Research: Employed in the study of protein structure, function, and interactions.
• Chemical Biology Tool: Facilitates the development of chemical probes and activity-based protein profiling (ABPP) reagents.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring specific chiral or functionalized amino acid derivatives.

Basic Information

Product Name	N2-Chloroacetyl-Glutamine
CAS No.	13139-62-3
Molecular Formula	C7H11ClN2O4
Molecular Weight	222.63 g/mol
Synonyms	N-Chloroacetyl-L-glutamine; L-Glutamine, N-(chloroacetyl)-; Chloroacetylglutamine; N-(Chloroacetyl)glutamine; 2-Chloro-N-[(4S)-4-amino-4-carboxybutanoyl]acetamide; (S)-2-(2-Chloroacetamido)-5-aminopentanedioic acid; N-Chloroacetylglutamine; Glutamine, N-chloroacetyl-
EINECS	Contact for details

Quality Control

Our N2-Chloroacetyl-Glutamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.