Description

Z-Met-Gly-Oh CAS NO 13139-55-4 is a high-purity, protected dipeptide building block, specifically N-Carbobenzoxy-L-methionylglycine, essential for advanced peptide synthesis. This compound provides a critical, chemically defined intermediate for researchers and manufacturers requiring precise control over peptide chain assembly and side-chain functionality. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for the development of novel therapeutic peptides, biochemical probes, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential construction of custom peptide sequences in research and GMP manufacturing.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Linker Chemistry: Serves as a building block for creating peptide-drug conjugates, diagnostic agents, and labeled biomolecules.
• Biochemical Research: Employed in enzymatic studies, substrate synthesis, and the preparation of specialized peptides for structure-activity relationship (SAR) studies.
• Custom Peptide Service Providers: A fundamental raw material for companies offering bespoke peptide synthesis services to academic and industrial clients.

Basic Information

Product Name	Z-Met-Gly-Oh
CAS No.	13139-55-4
Molecular Formula	C15H20N2O5S
Molecular Weight	340.39 g/mol
Synonyms	N-Carbobenzoxy-L-methionylglycine; Z-L-Methionylglycine; Z-Met-Gly-OH; Cbz-Met-Gly-OH; Nα-[(Benzyloxy)carbonyl]-L-methionylglycine; N-Cbz-L-methionylglycine; (2S)-2-[[(2S)-2-[(Benzyloxycarbonyl)amino]-4-(methylsulfanyl)butanoyl]amino]acetic acid; L-Methionine, N-[(benzyloxy)carbonyl]-, 1-glycyl ester
EINECS	Contact for details

Quality Control

Our Z-Met-Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material with specifications tailored to client requirements, including potential compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	-20.0° to -24.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.