Description

Z-Val-NH2 is a protected amino acid derivative, specifically the Cbz (carboxybenzyl) protected form of L-valine amide, with the CAS registry number 13139-28-1. This compound serves as a crucial chiral building block and intermediate in the synthesis of complex peptides, peptidomimetics, and active pharmaceutical ingredients (APIs). It is essential for research and production in pharmaceutical development, biotechnology, and fine chemical synthesis, where high-purity, enantiomerically pure intermediates are required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the valine residue with orthogonal protection.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel bioactive compounds.
• Fine Chemical Production: Utilized as a high-value intermediate in the custom synthesis of specialty chemicals and catalysts.

Basic Information

Product Name	Z-Val-NH2
CAS No.	13139-28-1
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.29 g/mol
Synonyms	N-Cbz-L-valinamide; Carbobenzoxy-L-valinamide; (S)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanamide; Z-L-Val-NH2; Cbz-Val-NH2; Nα-Carbobenzyloxy-L-valinamide; Benzyl N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamate; L-Valine, N-[(phenylmethoxy)carbonyl]-, amide
EINECS	Contact for details

Quality Control

Our Z-Val-NH2 CAS NO 13139-28-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccants or an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.