Description

Boc-Osu CAS NO 13139-12-3 is a highly versatile and widely used reagent in organic synthesis, specifically designed for the introduction of the tert-butoxycarbonyl (Boc) protecting group. Its core value lies in its exceptional reactivity and selectivity for amines under mild conditions, enabling the efficient synthesis of complex peptides and other sensitive molecules. This product is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable and high-purity intermediates for drug discovery and development.

Application

• Peptide Synthesis: Primary reagent for the protection of amino groups in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Key building block in the production of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Bioconjugation: Used to modify proteins, antibodies, and other biomolecules for research and therapeutic applications.
• Combinatorial Chemistry: Essential for creating diverse chemical libraries in high-throughput screening for drug discovery.
• Organic Synthesis: Protects amines during multi-step synthetic sequences, allowing for selective reactions at other functional sites.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and plant growth regulators.

Basic Information

Product Name	Boc-Osu
CAS No.	13139-12-3
Molecular Formula	C9H13NO6
Molecular Weight	231.20 g/mol
Synonyms	N-(tert-Butoxycarbonyloxy)succinimide; N-Boc-Oxy-succinimide; N-Boc-succinimide; N-(tert-Butoxycarbonyl)succinimide; Boc-OSu; N-Boc-Oxy-succinimide; N-Boc-OSu; tert-Butyl N-succinimidyl carbonate; 2,5-Pyrrolidinedione, 1-[[(1,1-dimethylethoxy)carbonyl]oxy]-
EINECS	236-085-6

Quality Control

Our Boc-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.