Description

(2'-Nitro)Phenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is a key protected glycosyl derivative, specifically designed as a sophisticated synthetic intermediate for advanced organic and medicinal chemistry. Its value lies in providing a reactive, selectively protected sugar scaffold that enables the controlled construction of complex carbohydrate-based molecules. This compound is essential for researchers and process chemists in pharmaceutical development, particularly for synthesizing novel glycoconjugates, glycomimetics, and other bioactive compounds where precise glycosylation is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and glycoconjugate vaccines.
• Glycobiology Research: Used in academic and industrial research to study glycosylation processes, enzyme mechanisms, and carbohydrate-protein interactions.
• Glycomimetic Synthesis: Serves as a precursor for creating glycomimetics, which are drug candidates designed to mimic natural sugars for therapeutic applications.
• Chemical Biology Probes: Employed in the development of labeled or tagged carbohydrate probes for diagnostic and imaging applications.
• Process Chemistry: Utilized in scale-up and optimization of glycosylation reactions for the production of carbohydrate-derived compounds.

Basic Information

Product Name	(2'-Nitro)Phenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside
CAS No.	13089-26-4
Molecular Formula	C21H26N2O11
Molecular Weight	482.44 g/mol
Synonyms	2'-Nitrophenyl 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; 2'-Nitrophenyl N-Acetyl-β-D-glucosaminide Triacetate; 2'-Nitrophenyl 2-Deoxy-2-acetamido-3,4,6-tri-O-acetyl-β-D-glucopyranoside; β-D-Glucopyranoside, 2'-nitrophenyl 2-(acetylamino)-2-deoxy-3,4,6-tri-O-acetyl-; PNP-β-GlcNAc Triacetate; 4-Nitrophenyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside (isomer); N-Acetyl-β-D-glucosaminide, 2'-nitrophenyl, peracetate
EINECS	Contact for details

Quality Control

Our (2'-Nitro)Phenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to verify stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent hydrolysis of the acetyl protecting groups. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.