Description

Iothalamate Meglumine is a high-purity, iodinated organic salt primarily used as a key contrast agent intermediate in diagnostic imaging. Its primary value lies in its ability to enhance X-ray visibility in medical procedures, enabling clear visualization of internal structures. This compound is essential for manufacturers in the pharmaceutical and diagnostic imaging industries, particularly for producing sterile injectable formulations for angiography and urography.

Application

• Primary intermediate in the synthesis of iodinated X-ray contrast media for medical diagnostics.
• Used in the formulation of injectable contrast agents for angiography (blood vessel imaging).
• Key component in agents for urography and pyelography (kidney and urinary tract imaging).
• Employed in the production of contrast media for computed tomography (CT) scans.
• Used in research and development of new diagnostic pharmaceutical formulations.
• Potential use in specialized veterinary diagnostic imaging applications.

Basic Information

Product Name	Iothalamate Meglumine
CAS No.	13087-53-1
Molecular Formula	C18H28I3N3O9
Molecular Weight	809.14 g/mol
Synonyms	Meglumine Iothalamate; Iothalamic Acid Meglumine Salt; Conray; Iothalamate N-Methylglucamine; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic acid compound with 1-deoxy-1-(methylamino)-D-glucitol; 1-Deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6-triiodo-N-methylisophthalamate; Meglumine salt of iothalamic acid; N-Methylglucamine iothalamate
EINECS	235-990-9

Quality Control

Our Iothalamate Meglumine is produced under strict quality management systems, targeting specifications suitable for pharmaceutical intermediate applications. Each batch is subjected to rigorous analytical testing, including HPLC for assay and impurity profile, residual solvent analysis, and identification tests. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
pH (5% solution)	6.5 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.