Description

Ethyl Trifluoropyruvate is a versatile fluorinated building block essential for advanced organic synthesis. Its unique trifluoromethyl and ester functionalities make it a critical reagent for introducing fluorine atoms into target molecules, enhancing their metabolic stability and lipophilicity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, including protease inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science: Serves as a monomer or precursor for specialty polymers and coatings with enhanced chemical resistance.
• Organic Synthesis Reagent: Employed in nucleophilic addition reactions, cyclizations, and as a precursor for other trifluoromethyl-containing compounds.
• Fluorine Chemistry Research: A fundamental reagent in academic and industrial labs for developing new fluorination methodologies.

Basic Information

Product Name	Ethyl Trifluoropyruvate
CAS No.	13081-18-0
Molecular Formula	C5H5F3O3
Molecular Weight	170.09 g/mol
Synonyms	Ethyl 3,3,3-Trifluoropyruvate; 3,3,3-Trifluoro-2-oxopropanoic Acid Ethyl Ester; Trifluoropyruvic Acid Ethyl Ester; Ethyl 2-Oxo-3,3,3-trifluoropropanoate; 2-Oxo-3,3,3-trifluoropropionic Acid Ethyl Ester; Ethyl α-Keto-β,β,β-trifluoropropionate; TFPE
EINECS	Contact for details

Quality Control

Our Ethyl Trifluoropyruvate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.