Description

(2S)-2-Acetamido-5-Oxo-Pentanoic Acid CAS NO 13074-21-0 is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the production of complex pharmaceutical actives and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries for developing novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of protease inhibitors, enzyme inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in the preparation of modified peptides and peptidomimetics for drug discovery and biochemical research.
• Bioconjugation Chemistry: Serves as a precursor for linkers and functional handles in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed as a tool compound or precursor in studying enzyme mechanisms and metabolic pathways.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals and catalysts.

Basic Information

Product Name	(2S)-2-Acetamido-5-Oxo-Pentanoic Acid
CAS No.	13074-21-0
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	N-Acetyl-L-glutamic acid 5-semialdehyde; L-2-Acetamidoglutaric acid 5-semialdehyde; (S)-2-Acetamido-5-oxopentanoic acid; 5-Oxo-L-norleucine N-acetate; N-Acetyl-5-oxo-L-norleucine; Ac-5-oxo-Nle-OH; N-Acetyl-L-α-aminoadipic acid δ-semialdehyde
EINECS	Contact for details

Quality Control

Our (2S)-2-Acetamido-5-Oxo-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.