Description

3-Bromo-2-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both bromine and hydroxyl substituents ortho to the nitrile group, makes it a valuable building block for constructing complex molecules. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with benzofuran or benzoxazole cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors for biochemical and pharmacological studies.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-Hydroxybenzonitrile
CAS No.	13073-28-4
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	2-Hydroxy-3-bromobenzonitrile; 3-Bromo-2-hydroxybenzenecarbonitrile; 3-Bromosalicylonitrile; 2-Cyano-6-bromophenol; 6-Bromo-2-hydroxybenzonitrile; 3-Bromo-2-cyanophenol; o-Cyano-m-bromophenol
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Hydroxybenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.