Description

n-Cbz-Dl-Tryptophan is a protected derivative of the essential amino acid tryptophan, where the amine group is shielded by a carboxybenzyl (Cbz) protecting group. This modification is critical for its primary role as a key chiral building block and intermediate in the synthesis of complex peptides and pharmaceutical compounds. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise control over molecular structure is required.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate tryptophan residues while protecting the amine functionality.
• Biochemical Research: Serves as a reagent in proteomics research, enzyme studies, and the development of novel biochemical probes.
• Chiral Compound Production: Acts as a starting material for the preparation of enantiomerically pure tryptophan derivatives and other chiral molecules.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals and specialty chemicals.

Basic Information

Product Name	n-Cbz-Dl-Tryptophan
CAS No.	13058-16-7
Molecular Formula	C20H20N2O4
Molecular Weight	352.39 g/mol
Synonyms	N-Carbobenzoxy-DL-tryptophan; Nα-Cbz-DL-Tryptophan; Z-DL-Trp-OH; DL-N-Carbobenzoxytryptophan; Benzyl N-(DL-1H-indol-3-ylmethylcarbamoyl)carbamate; (RS)-2-[[(Benzyloxy)carbonyl]amino]-3-(1H-indol-3-yl)propanoic acid; Nα-Benzyloxycarbonyl-DL-tryptophan
EINECS	Contact for details

Quality Control

Our n-Cbz-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (DL Ratio)	~ 1:1 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.