Description

Benzylpenicilloic Acid is a key intermediate and degradation product derived from benzylpenicillin (penicillin G). This compound is of significant importance in pharmaceutical research and quality control, particularly for the analysis and stability testing of penicillin-based antibiotics. It serves as a critical reference standard for identifying and quantifying penicillin impurities and degradation pathways. Industries requiring this high-purity chemical include pharmaceutical R&D, analytical laboratories, and manufacturers of antibiotic active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of benzylpenicillin and its related substances in compliance with pharmacopeial monographs (e.g., USP, EP).
• Impurity Profiling: Essential for the analysis of degradation products and process-related impurities in penicillin G and semi-synthetic penicillin manufacturing.
• Stability-Indicating Methods: Employed in the development and validation of HPLC and other analytical methods to monitor the stability of penicillin formulations.
• Metabolic Studies: Used in research to study the metabolism and degradation pathways of penicillin antibiotics in biological systems.
• Quality Control Laboratories: A critical reagent for in-house quality testing of raw materials and finished antibiotic products to ensure safety and efficacy.
• Academic and Clinical Research: Supports investigative studies on antibiotic resistance, mechanism of action, and the chemical behavior of β-lactam compounds.

Basic Information

Product Name	Benzylpenicilloic Acid
CAS No.	13057-98-2
Molecular Formula	C16H20N2O5S
Molecular Weight	352.41 g/mol
Synonyms	Penicilloic Acid (Benzylpenicillin); (2S,5R,6R)-6-[(2R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Benzylpenicillinic Acid; Penicillin G Penicilloate; Penicilloyl-Penicillin; 6-APA Derivative; Penicillin G Degradation Product
EINECS	Contact for details

Quality Control

Our Benzylpenicilloic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical analysis. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific pharmacopeial (USP/EP) or customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.