Description

Fusidic Acid Acyl β-D-Glucuronide is a crucial metabolite and reference standard derived from the antibiotic fusidic acid. This compound is essential for pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and bioanalytical method validation. It is primarily utilized by research institutions, pharmaceutical manufacturers, and contract research organizations (CROs) engaged in the development and quality control of fusidic acid-based therapeutics.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification and quantification of fusidic acid metabolites in biological matrices.
• Drug Metabolism & Pharmacokinetics (DMPK) Studies: Used as a critical analyte to investigate the metabolic pathways, clearance, and bioavailability of fusidic acid.
• Bioanalytical Method Development: Essential for developing and validating sensitive HPLC, LC-MS, or LC-MS/MS assays for therapeutic drug monitoring and clinical studies.
• Impurity Profiling: Acts as a known impurity or degradation product reference in the stability testing and quality control of fusidic acid active pharmaceutical ingredients (APIs) and finished dosage forms.
• Toxicological Research: Employed in studies to understand the safety profile and potential toxicological implications of fusidic acid metabolites.

Basic Information

Product Name	Fusidic Acid Acyl β-D-Glucuronide
CAS No.	13013-66-6
Molecular Formula	C37H56O12
Molecular Weight	692.84 g/mol
Synonyms	Fusidic Acid Glucuronide; Fusidic Acid Acyl-β-D-Glucuronide; Fusidic Acid β-D-Glucuronide; (3β,4α,8α,11α,14α,17β)-17-[(2S,3S,4R,5R,6S)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,11-dihydroxy-4,8,14-trimethyl-18-nor-5α,8α,9β,13α,14β-androsta-17-carboxylic acid 1,10-seco-1(10→5)abeo-5,10:9,11-diepoxy-17-(2-oxoethyl)-10,13-dimethyl-3-oxo-4,5-seco-5α-gona-1(10),2,4,11-tetraene-4-carboxylate; Fusidic Acid Metabolite; FA-Gluc
EINECS	Contact for details

Quality Control

Our Fusidic Acid Acyl β-D-Glucuronide is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for use as a reference standard. A detailed Certificate of Analysis (COA) specifying batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.