Description

Northioridazine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical essential for the development and synthesis of advanced therapeutic agents. Its primary value lies in its role as a key building block for creating phenothiazine-derived compounds, which are critical in modern medicinal chemistry. This product is specifically required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on neuropharmacology and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of phenothiazine-based antipsychotic and neuroleptic agents.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and structure-activity relationship (SAR) analysis.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex drug molecules targeting the central nervous system.
• Biochemical Research: Utilized in studies investigating dopamine receptor interactions and neurological pathways.

Basic Information

Product Name	Northioridazine Hydrochloride
CAS No.	13002-81-8
Molecular Formula	C23H30N2S2•HCl
Molecular Weight	443.08 g/mol
Synonyms	Nor Thioridazine Hydrochloride; Desmethylthioridazine Hydrochloride; 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride; 2-Methylmercapto-10-[2-(1-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride; Northioridazine HCl; Nor-Thioridazine HCl; Major Metabolite of Thioridazine Hydrochloride
EINECS	Contact for details

Quality Control

Our Northioridazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.