Description

β-Bungarotoxin is a potent, presynaptically active neurotoxin isolated from the venom of the Taiwanese banded krait (*Bungarus multicinctus*). This highly specific compound is a critical research tool for studying neurotransmitter release mechanisms, particularly at the neuromuscular junction. It is essential for neuroscientists, pharmacologists, and toxicologists in academic, pharmaceutical, and biotechnology sectors conducting fundamental research on synaptic function, neurotoxicity, and potential therapeutic targets.

Application

• Neuroscience Research: A primary tool for investigating the molecular mechanisms of acetylcholine release and presynaptic function.
• Pharmacology & Toxicology Studies: Used to model neurotoxic effects and study the action of neurotoxins on synaptic transmission.
• Ion Channel & Receptor Research: Employed in electrophysiological studies to block specific potassium channels, aiding in the characterization of channel subtypes.
• Drug Discovery Platforms: Serves as a reference standard in screening assays for compounds that modulate neurotransmitter release or protect against neurotoxicity.
• Biochemical Assay Development: Used as a precise biochemical tool to probe protein-protein interactions involved in the synaptic vesicle cycle.
• Antivenom Research & Development: Acts as a key antigen and reference toxin in the development and efficacy testing of antivenoms.

Basic Information

Product Name	β-Bungarotoxin
CAS No.	12778-32-4
Molecular Formula	Information on request
Molecular Weight	Information on request
Synonyms	β-Bungarotoxin; Bungarotoxin β-chain; Bungarus multicinctus venom toxin; Presynaptic neurotoxin; β-neurotoxin; Toxin BmK; β-Bgt
EINECS	Contact for details

Quality Control

Our β-Bungarotoxin is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is characterized for purity and identity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, biological activity (where applicable), and analytical results is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -70°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity	Assessed by specific assay (e.g., mouse LD50, in vitro blockade)
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers or saline

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.