Description

Scorpion Toxin I, Androctonus is a highly specific, biologically active peptide neurotoxin isolated from the venom of the *Androctonus* scorpion species. This compound is of significant value for its potent and selective interaction with voltage-gated sodium channels, making it a critical tool for neurological and pharmacological research. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on ion channel studies, neurotoxin mechanisms, and the development of novel therapeutic agents or analytical standards.

Application

• Neuroscience Research: As a selective modulator for studying the structure, function, and kinetics of voltage-gated sodium channels (Nav channels) in neuronal cells.
• Pharmacological Probe Development: Utilized in high-throughput screening (HTS) assays to identify and characterize new channel blockers or modulators for drug discovery.
• Toxin-Antitoxin Studies: Serves as a reference standard in the development and validation of antivenoms and therapeutic neutralizing antibodies.
• Biochemical Reagent: Used in protein interaction studies, receptor binding assays, and as a ligand for affinity purification of specific channel subtypes.
• Diagnostic Tool Manufacturing: Incorporated into specialized diagnostic kits and biosensors for detecting specific biological activities or for quality control in biopharmaceutical production.
• Academic & Industrial R&D: Essential for basic research in toxicology, electrophysiology, and cellular signaling pathways within university and corporate laboratories.

Basic Information

Product Name	Scorpion Toxin I, Androctonus
CAS No.	12584-90-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Androctonus australis Hector toxin I; AaH I; Toxin I (Androctonus australis); Scorpion α-toxin AaH I; Androctonus australis neurotoxin I; Sodium channel neurotoxin; CAS 12584-90-6
EINECS	Contact for details

Quality Control

Our Scorpion Toxin I, Androctonus is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, including purity assessment and functional activity verification. Certificates of Analysis (COA) detailing specific purity, bioactivity (where applicable), and analytical results are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Assayed and reported per COA
Moisture Content (KF)	≤ 5.0%
Endotoxin Level	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.