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Parathyroid Hormone (1-34), Bovine CAS NO 12583-68-5


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CAS No.:12583-68-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Parathyroid Hormone (1-34), Bovine is a bioactive fragment of the native parathyroid hormone, consisting of the first 34 amino acids, which is sufficient for full biological activity. This high-purity peptide is critical for research into calcium and phosphate metabolism, bone physiology, and endocrine signaling pathways. It is an essential biochemical tool for pharmaceutical R&D, academic research in endocrinology, and as a reference standard in analytical laboratories.

Application

  • Biomedical Research: Fundamental studies on bone remodeling, calcium homeostasis, and renal function.
  • Drug Discovery & Development: Screening for PTH receptor agonists/antagonists and investigating anabolic therapies for osteoporosis.
  • Reference Standard: Used in analytical methods (HPLC, bioassays) for quality control and quantification of related peptide products.
  • Cell Culture & In Vitro Studies: Stimulation of cAMP production in osteoblast and kidney cell lines to study signal transduction.
  • Endocrinology Studies: Investigating the pathophysiology of hyperparathyroidism and hypoparathyroidism.
  • Peptide Chemistry: Serves as a model compound for studying peptide stability, formulation, and delivery.

Basic Information

Product Name Parathyroid Hormone (1-34), Bovine
CAS No. 12583-68-5
Molecular Formula C₁₈₁H₂₉₁N₅₅O₅₁S₂
Molecular Weight ~4117.8 g/mol
Synonyms Bovine PTH (1-34); Parathyrin (1-34), bovine; PTH 1-34 (bovine); Teriparatide (bovine sequence); N-terminal parathyroid hormone fragment; Parathyroid hormone fragment 1-34 (bovine); Endocrine peptide 1-34
EINECS Contact for details

Quality Control

Our Parathyroid Hormone (1-34), Bovine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Peptide Content ≥ 80.0% (by amino acid analysis)
Water Content (KF) ≤ 5.0%
Acetate Content (HPLC) ≤ 10.0%
Biological Activity Stimulates cAMP production in suitable cell lines (Data available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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