Description

2-Chloro-5-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a chloro substituent, makes it a valuable intermediate for constructing complex molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with potential antibacterial or antitumor activity.
• Agrochemical Synthesis: Building block for manufacturing herbicides, fungicides, and insecticides, leveraging its reactive sites for structural modification.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized azo dyes and high-performance pigments.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and other functional organic materials.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for creating biaryl structures.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-5-Nitrobenzonitrile
CAS No.	11588-02-6
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	5-Nitro-2-chlorobenzonitrile; 2-Chloro-5-nitrobenzenecarbonitrile; Benzonitrile, 2-chloro-5-nitro-; 2-Chloro-5-cyanomitrobenzene; 2-Chloro-5-nitro-benzonitrile; NSC 403119; 2-Chlor-5-nitro-benzonitril (German)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, NMR, and other relevant methods. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 149 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.