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Boc-D-2,4-Dichlorophenylalanine CAS NO 114873-02-0


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CAS No.:114873-02-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Boc-D-2,4-Dichlorophenylalanine is a protected, non-natural amino acid derivative essential for advanced peptide synthesis. This compound matters because it provides a chiral building block with enhanced stability and reactivity control, crucial for constructing complex bioactive molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel peptide-based therapeutics, diagnostics, and research biochemicals.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
  • Peptide Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-isomer of 2,4-dichlorophenylalanine into research peptides.
  • Proteomics & Biochemistry: Serves as a building block for creating custom peptides used in enzyme studies, receptor binding assays, and structure-activity relationship (SAR) research.
  • Chemical Biology Tool Development: Employed in the design and synthesis of peptide probes, inhibitors, and labeled compounds for cellular and molecular biology.
  • Agrochemical Research: Potential intermediate in the development of novel peptide-mimetic agrochemicals.

Basic Information

Product Name Boc-D-2,4-Dichlorophenylalanine
CAS No. 114873-02-0
Molecular Formula C₁₄H₁₇Cl₂NO₄
Molecular Weight 334.20 g/mol
Synonyms N-(tert-Butoxycarbonyl)-D-2,4-dichlorophenylalanine; Boc-D-2,4-Dichloro-Phe-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid; D-Boc-2,4-Dichlorophenylalanine; Boc-D-2,4-DCP; N-Boc-D-2,4-dichlorophenylalanine; tert-Butyloxycarbonyl-D-2,4-dichlorophenylalanine
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Quality Control

Our Boc-D-2,4-Dichlorophenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) documenting identity, purity, and specific impurities are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Chiral Purity (HPLC) ≥99.0% de
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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