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Calcitonin, Rat CAS NO 11118-25-5


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CAS No.:11118-25-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Calcitonin, Rat is a synthetic polypeptide hormone identical to the endogenous calcitonin found in rats. This high-purity peptide is essential for researchers in endocrinology and bone metabolism studies, providing a critical tool for investigating calcium homeostasis and related physiological pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic disease research and drug discovery.

Application

  • Biomedical Research: Fundamental studies on calcium and phosphate regulation in rodent models.
  • Endocrinology Studies: Investigation of hormonal feedback mechanisms involving the thyroid and parathyroid glands.
  • Bone Metabolism Research: In vitro and in vivo assays to study osteoclast activity, bone resorption, and osteoporosis mechanisms.
  • Pharmacological Assays: Standard and calibration reagent for screening and evaluating potential therapeutic compounds targeting the calcitonin receptor.
  • Diagnostic Development: Used as a reference standard in the development and validation of immunoassays (e.g., ELISA, RIA).
  • Comparative Physiology: Studies comparing the structure, function, and efficacy of calcitonin across different species.

Basic Information

Product Name Calcitonin, Rat
CAS No. 11118-25-5
Molecular Formula C₁₄₅H₂₄₀N₄₄O₄₈S₂
Molecular Weight 3416.8 g/mol
Synonyms Rat Calcitonin; Salmon Calcitonin I; sCT; Calcitonin (salmon); Thyrocalcitonin (salmon); CAS 47931-85-1 (salmon calcitonin variant); Calcitonin Gene-Related Peptide I (CGRP-I) related; Hypocalcemic hormone
EINECS Contact for details

Quality Control

Our Calcitonin, Rat is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for critical research applications. Certificates of Analysis (COA) detailing purity, peptide content, and biological activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Peptide Content ≥ 80.0% (by weight)
Water Content (KF) ≤ 5.0%
Biological Activity Assayed (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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