Description

C-Peptide (1-35) (Human) is a synthetic polypeptide fragment corresponding to the connecting peptide region of human proinsulin. This high-purity biochemical is a critical reference standard and research tool for studies in diabetes, insulin biosynthesis, and metabolic disorders. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors requiring precise and reliable biological reagents.

Application

• Biomedical Research: Used as a key reference standard in diabetes research to study insulin processing, β-cell function, and C-peptide physiology.
• Diagnostic Development: Serves as a critical calibrator and antigen in the development and validation of immunoassays (ELISA, RIA) for measuring endogenous C-peptide levels.
• Pharmaceutical R&D: Employed in preclinical studies investigating the therapeutic potential of C-peptide in diabetic complications, such as neuropathy and nephropathy.
• Quality Control: Acts as a system suitability standard in analytical methods (e.g., HPLC, LC-MS) for peptide purity and identity testing within GMP environments.
• Cell Biology Studies: Utilized in in vitro assays to examine cellular signaling pathways and receptor interactions related to proinsulin-derived peptides.

Basic Information

Product Name	C-Peptide (1-35) (Human)
CAS No.	11097-48-6
Molecular Formula	C164H265N49O52
Molecular Weight	~ 3678.2 g/mol
Synonyms	Human C-Peptide; Proinsulin C-Peptide (Human); Connecting Peptide; Insulin C-Peptide; C-Peptide (Human); C-Peptide 1-35; H-CP; CAS 11097-48-6
EINECS	Contact for details

Quality Control

Our C-Peptide (1-35) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.